RNAseq analysis of SARS-CoV-2 infection of iAT2 cells

Analysis of histone mimicry by SARS-CoV-2 Orf8 encoded protein SARS-CoV-2 WT virus, Orf8 deletion virus, or mock infection of A549-ACE cells was performed and RNA was collected at 24 or 48 hours after infection

本研究针对分别感染新型冠状病毒（SARS-CoV-2）野生型毒株、Orf8缺失毒株，或进行空白感染的A549-ACE细胞（A549-ACE cells），开展由该病毒Orf8编码蛋白介导的组蛋白模拟（histone mimicry）分析，并于感染后24小时或48小时收集细胞RNA。