Additional file 1: Table S1. of Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation

Sequencing statistics summary. Table S2. Genome feature association of filtered variant-removed CpGs for adipose and blood. Table S3. Characteristics of unmethylated (UMR) and low-methylated regions (LMR) in adipose and blood. Table S4. Number of invariable sites in filtered datasets at various minimum coverages. Table S5. pDMR statistics in adipose and blood. Table S6. Result of the TFBS motif analysis using the HOMER software. Table S7. MZ2 vs. MZ3-derived significant DMCs overlapping known smoking methylation loci. Table S8. Genetic and non-genetic effect of CpG methylation. Table S9. Overall detected CpH methylation per tissue and strand. (XLSX 56 kb)

测序统计汇总。表S2：脂肪组织与血液中经过滤并剔除变异的CpG位点（CpG）的基因组特征关联分析。表S3：脂肪组织与血液中未甲基化区域（UMR，unmethylated region）和低甲基化区域（LMR，low-methylated region）的特征。表S4：不同最低覆盖度阈值下过滤后数据集的不变位点数量。表S5：脂肪组织与血液中的pDMR统计结果。表S6：采用HOMER软件开展的转录因子结合位点（TFBS，transcription factor binding site）基序分析结果。表S7：由MZ2与MZ3得到的显著差异甲基化CpG位点（DMCs，differentially methylated CpGs）与已知吸烟相关甲基化位点的重叠情况。表S8：CpG甲基化的遗传与非遗传效应。表S9：各组织及链方向的总CpH甲基化检测概况。（XLSX格式，大小56 KB）