16s rRNA gene amplicon sequencing for BCAA study

Preterm birth has been associated with alterations to the microbiome. Nutritional supplementation is commonly employed clinically to support the growth of preterm infants. There is little information on how nutritional supplementation interacts with the developing microbiome of the small intestine, the major site for nutrient metabolism and absorption. The objectives of this study were to investigate the effect of preterm birth and nutritional supplementation on the mucosal and luminal microbiota along the gastrointestinal tract (GIT) of preterm lambs.

早产与微生物组（microbiome）的改变密切相关。临床中常采用营养补充措施以支持早产婴儿的生长发育。目前关于营养补充剂如何与作为营养代谢与吸收主要场所的小肠内发育中的微生物组相互作用的相关信息甚少。本研究旨在探究早产与营养补充剂对早产羔羊胃肠道（gastrointestinal tract, GIT）各段黏膜菌群与肠腔菌群的影响。