Expression Profiles of PMH treated with 7µM of the genotoxic compound cisplatin

The transcriptomic changes induced in primary mouse hepatocytes (C57BL/6 ) by 7µM of cisplatin after treatment for 24 and 48h The study investigated differential gene expression in PMH mRNA following 24 and 48 hours of exposure to 7µM of cisplatin and its solvent. Three biological replicates per compound/solvent. In total 12 arrays.

本数据集记录了7μM顺铂（cisplatin）分别处理24小时与48小时后，在C57BL/6品系原代小鼠肝细胞（primary mouse hepatocytes，缩写PMH）中诱导产生的转录组变化。本研究针对原代小鼠肝细胞的mRNA，分析了经7μM顺铂及其溶剂对照分别暴露24、48小时后的差异基因表达水平。每组处理（顺铂/溶剂对照）均设置3次生物学重复，实验总计包含12张基因芯片阵列。