Caregiver Health and Household Info by Visit in Adolescent Master Protocol, PH200

Caregiver Health and Household Info by Visit Analysis File (July 2024). Data updated in 2024 in DASH to include the follow-up time points through the final participant visit in 2020.
Study Description
The PHACS AMP study is designed to define the impact of HIV infection and antiretroviral therapy on pre-adolescents and adolescents with perinatal HIV infection. Domains investigated include growth and sexual maturation; metabolic risk factors for cardiovascular disease; cardiac function; bone health; neurologic, neurodevelopment, language, hearing, and behavioral function; and adolescent gynecology and HPV infection. Biospecimens are available. AMP includes 451 perinatally HIV-infected (PHIV) youth and 227 perinatally HIV-exposed uninfected (PHEU) youth, age 6 to 17 years at study entry. [587 caregivers also enrolled to provide information on their children.]

按访视整理的看护者健康与家庭信息分析文件（2024年7月版）。本数据集于2024年在DASH系统中完成更新，纳入了截至2020年最后一次受试者访视的全部随访时间点数据。
研究概况
PHACS AMP研究旨在明确人类免疫缺陷病毒（Human Immunodeficiency Virus, HIV）感染与抗反转录病毒治疗对围生期HIV感染青少年及青春期前儿童的影响。本研究涵盖的考察领域包括生长发育与性成熟、心血管疾病代谢危险因素、心脏功能、骨骼健康、神经与神经发育、语言、听力及行为功能，以及青少年妇科与人类乳头瘤病毒（Human Papillomavirus, HPV）感染情况。可提供生物样本。该研究共纳入451名围生期HIV感染（perinatally HIV-infected, PHIV）青少年与227名围生期HIV暴露但未感染（perinatally HIV-exposed uninfected, PHEU）青少年，入组时年龄为6至17岁。另有587名看护者入组，为其子女提供相关信息。