Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells. Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells

We report the gene expression profiles of gastric squamous-columnar junction cancer derived from the mice with conditionally inactivation of Trp53 and Rb1 genes in Lgr5+ cells Overall design: Examination of gene expression profiles between 5 cancer samples and 3 normal control tissues

本研究报道了在Lgr5阳性细胞(Lgr5+ cells)中条件性失活Trp53与Rb1基因的小鼠所诱导的胃鳞状-柱状连接部癌的基因表达谱。实验设计概述：对5份癌样本与3份正常对照组织的基因表达谱进行比较分析。