ABPM anxiety disorders

Fifty consecutive outpatients with anxiety disorders and personality disorders who participated in intensive group psychotherapy were included. Diagnoses were made according to DSM-IV-TR criteria using the PSE-10 questionnaire. Out of 50 patients, 17 were diagnosed with Panic Disorder and 21 with Generalized Anxiety Disorder. The control group consisted of 40 healthy people from the general population.
None of the people included in any of the groups had a diagnosis of hypertension nor cardiovascular disease or any serious somatic disease. To study the 24-hour automatic monitoring of blood there were used ABPM recorders (ambulatory blood pressure measurement) Medilog Accutracker DX that combine auscultatory and ECG techniques. For the day record (from 7.01 to 22.00) time interval was 20 minutes and for the night record (from 22.01 to 7.00) it was 30 minutes. For the analysis of the obtained record, the ABP Suprima – Medilog Oxford system was used. The result of this phase of the analysis was the digital record containing the set of systolic and diastolic pressure values. Taking into consideration the diverse circadian activity of the studied people, the comparison of average blood pressure during periods of day and night – excluding waking up and falling asleep – was made. Based on the analysis of the studied people’s circadian activity, to estimate the average blood pressure during the day, the period between 10 a.m. and 8 p.m. was assumed, and to estimate the average blood pressure during the night, the period between midnight and 6 a.m. was assumed.
variables: variables: age, sex, dwelling (1 city>0.5 mln, 2 small city or suburbs) education (1 primary, 2 secondary, 3 higer), work (1 working, 2 student, 3 does not work), group (2-panic attacs, 1-withot panic attacs, 0-healthy controls), diag_ (1-panic, 2-GAD, 3-other), valid (0 rejected due to diagnosis, 1 included), DSM-IV-TR
(diagnoses DSM-IV-TR code), ICD-10 (diagnoses ICD-10 code), SDBP (mean systolic day blood pressure), SNBP mean systolic night blood pressure), SDN_diff (SDBP-SNBP), s_dipper (SDN_diff%), DDBP (mean diastolic day blood pressure), DNBP (mean diastolic night blood pressure), DDN_diff (DDBP-DNBP) d_dipper d_dipper (DDN_diff%), s_dipp (systolic dipper), d_dipp (diastolic dipper), t_dipp (systolic and diastolic dipper), SD_ndipp (reverse dipper), BPs_7_04... (systolic BP, hour_sampleID) BPd_7_2... (diastolic BP, hour_sample ID)
i.e. BPs_7_05 means systolic blood pressure value at 7 am with index 04
BPd_7_2 means diastolic blood pressure valus at 7 am with index 2
The indices corresponding to the same measuring point are the same
This version of data contains ICD-10 diagnoses and dwelling, education and work wariables

本研究纳入50例连续就诊的焦虑障碍及人格障碍门诊患者，所有受试者均参与了密集型团体心理治疗。所有受试者的诊断均依据《精神障碍诊断与统计手册第四版修订版》（DSM-IV-TR）标准，采用PSE-10量表进行评估。50例患者中，17例被诊断为惊恐障碍（Panic Disorder），21例被诊断为广泛性焦虑障碍（Generalized Anxiety Disorder）。对照组纳入40名来自普通人群的健康个体。

两组受试者均未被诊断为高血压、心血管疾病或任何严重躯体疾病。为开展24小时动态血压监测研究，本研究采用了结合听诊法与心电图（ECG）技术的Medilog Accutracker DX型动态血压监测（ambulatory blood pressure measurement, ABPM）记录仪。日间监测时段为7:01至22:00，采样间隔为20分钟；夜间监测时段为22:01至次日7:00，采样间隔为30分钟。采用ABP Suprima–Medilog Oxford系统对获取的监测数据进行分析，该分析阶段的输出结果为包含收缩压与舒张压数值集合的数字化记录文件。

考虑到受试者的昼夜活动节律存在差异，本研究在比较日间与夜间平均血压时，排除了觉醒与入睡时段。基于对受试者昼夜活动节律的分析，本研究将日间平均血压的估算时段设定为上午10:00至晚上8:00，夜间平均血压的估算时段设定为午夜至次日上午6:00。

### 变量说明
1. 人口学与社会学变量：
- 年龄（age）、性别（sex）、居住类型（dwelling：1=人口超过50万的大城市，2=小城市或郊区）
- 受教育程度（education：1=初等教育，2=中等教育，3=高等教育）
- 就业状态（work：1=在职，2=学生，3=无业）
- 分组（group：2=惊恐发作组，1=无惊恐发作组，0=健康对照组）
- 诊断类别（diag_：1=惊恐障碍，2=广泛性焦虑障碍，3=其他障碍）
- 有效性标记（valid：0=因诊断不符合要求被剔除，1=纳入研究）
2. 诊断编码变量：
- DSM-IV-TR诊断编码（DSM-IV-TR）
- ICD-10诊断编码（ICD-10）
3. 血压节律参数：
- 日间平均收缩压（SDBP, mean systolic day blood pressure）
- 夜间平均收缩压（SNBP, mean systolic night blood pressure）
- 日间-夜间收缩压差（SDN_diff = SDBP - SNBP）
- 收缩压昼夜差值百分比（s_dipper = SDN_diff%）
- 日间平均舒张压（DDBP, mean diastolic day blood pressure）
- 夜间平均舒张压（DNBP, mean diastolic night blood pressure）
- 日间-夜间舒张压差（DDN_diff = DDBP - DNBP）
- 舒张压昼夜差值百分比（d_dipper = DDN_diff%）
- 收缩压勺型曲线（s_dipp, systolic dipper）
- 舒张压勺型曲线（d_dipp, diastolic dipper）
- 收缩压与舒张压均为勺型曲线（t_dipp, systolic and diastolic dipper）
- 反勺型曲线（SD_ndipp, reverse dipper）
- 按采样时刻标记的收缩压数据：BPs_小时_样本ID，例如BPs_7_04代表上午7时、样本索引为04的收缩压数值
- 按采样时刻标记的舒张压数据：BPd_小时_样本ID，例如BPd_7_2代表上午7时、样本索引为2的舒张压数值
注：同一测量点的采样索引相同。

本版本数据集包含ICD-10诊断编码以及居住类型、受教育程度与就业状态变量。