Allergenic Fragrances Analysis in Brazilian Perfumes by Headspace Solid Phase Microextraction and Gas Chromatography-Mass Detector (HS-SPME-GC-MS)

Perfumes are products mainly consisting of ethyl alcohol, water and fragrance. These fragrances are responsible for characterizing the pleasant and unique odor of each perfume. Among the fragrances, we highlight a group of fragrances which can cause contact allergy, leading to dermatitis. Brazilian and the European law state that when these concentrations of allergenic fragrances exceed the limit of 0.01% for non-rinse products and 0.001% for products with rinsing, the manufacturer is obliged to discriminate on its label their presence. This work aims to quantify allergic fragrances in original and Brazilian perfume using solid-phase microextraction and analyze by gas chromatography-mass detector.

香水是以乙醇、水与香精为主要成分的产品，这类香精赋予每款香水独特且宜人的气味特征。其中，一类可引发接触性皮炎的致敏香精尤为值得关注。巴西与欧盟法规明确规定：当免洗类产品中致敏香精浓度超过0.01%，或需冲洗类产品中该类香精浓度超过0.001%时，生产商必须在产品标签上标注其含有此类香精。本研究采用固相微萃取（solid-phase microextraction）技术，对原装香水与巴西本土香水中的致敏香精进行定量分析，并通过气相色谱-质谱检测器（gas chromatography-mass detector）完成检测分析。