Associations between 82 lipid ratios and markers of obesity in the Busselton Health Study.

Linear regression analysis, adjusting for age and sex, was performed between 82 lipid ratios and various markers of obesity in the BHS cohort (n = 4,492). 1Lipid nomenclature is read as follows: letters denote the head group; () brackets denote the sum composition of the lipid measured including total number of carbons and double bonds; [] denote the position of the acyl chain; n3 and n6 denote omega-3 and omega-6 poly-unsaturated fatty acid species; 2SD-change denotes the standard deviation change per unit of waist circumference (WC), body-mass-index (BMI) or waist–hip ratio (WHR); 3p-gain was calculated by dividing the lowest p-value among the lipid species used in the ratio by the p-value of the lipid ratio. The p-gain was deemed significant if it exceeded 10 × the number of ratios tested (p-gain >820).
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针对BHS队列（n=4492）中的82种脂质比值（lipid ratios）与各类肥胖标志物之间的关联，本研究开展了校正年龄与性别因素的线性回归分析。
1 脂质命名规则如下：字母代表头部基团；圆括号()表示所检测脂质的总组成，包含总碳原子数与双键数；方括号[]表示酰基链的位置；n3与n6分别代表Omega-3与Omega-6多不饱和脂肪酸种类；
2 SD-change（标准差变化量）指每单位腰围（WC, waist circumference）、体质量指数（BMI, body-mass-index）或腰臀比（WHR, waist–hip ratio）所对应的标准差变化；
3 p-gain（p增益值）通过将该比值所使用的各脂质组分中最低p值除以该脂质比值的p值计算得到。当p-gain超过检测比值总数的10倍（即p-gain>820）时，判定该结果具有统计学显著性。
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