MBIRA-pilot (Mortality from Bacterial Infections Resistant to Antibiotics). MBIRA-pilot

Isolates from a pilot of the first multi-national prospective observational study to better understand the mortality burden due to AMR in bloodstream infections in sub-Saharan Africa.The MBIRA project is focussed on bloodstream infections (=bacteraemia) caused by Gram-negative enteric bacteria (Enterobacteria, such as E. coli and Klebsiella pneumoniae) and includes patients of all age groups, from neonates to adults. The aim is to gather data across a range of hospitals in sub-Saharan Africa to inform larger global burden of disease analyses.

本数据集的分离菌株来自首个多国前瞻性观察研究的试点项目，该研究旨在深入解析撒哈拉以南非洲地区由抗菌药物耐药性（Antimicrobial Resistance, AMR）引发的血流感染所导致的死亡负担。MBIRA项目聚焦于由革兰阴性肠杆菌科细菌（Enterobacteria，如大肠埃希菌、肺炎克雷伯菌）引发的血流感染（即菌血症，bacteraemia），研究对象覆盖从新生儿至成年人的全年龄段患者。本研究的核心目标为在撒哈拉以南非洲的多家医院收集相关数据，为更大规模的全球疾病负担分析提供科学依据。