Effects of ATP6V1D knockdown on transcriptome in Hepatocellular Carcinoma PLC/PRF/5 cells

To explore the underlying mechanism of ATP6V1D in HCC progression, we performed RNA sequencing (RNA-seq) in shNC cells and shATP6V1D cells (n=3) to clarify the overall changes in the transcriptome after ATP6V1D knockdown.

为探究ATP6V1D在肝细胞癌（Hepatocellular Carcinoma, HCC）进展中的潜在分子机制，本研究对短发夹RNA阴性对照（shNC）细胞及靶向ATP6V1D的短发夹RNA（shATP6V1D）细胞进行了RNA测序（RNA-seq）实验（每组n=3），以阐明ATP6V1D敲低后转录组的整体表达变化。