Analysis of Allelic Association of SNP rs9943582 with LVSD among the CAD population.

Freq _A: Frequency of A allele. LVSD: left ventricle systolic dysfunction, LVEF: left ventricle eject fraction.*Uncorrected P value and odds ratio (OR) using Chi-square tests with Pearson’s 2×2.†Adjusted P value by multivariate logistic regression analysis for potential confounders including age, gender, smoking, hypertension, diabetes mellitus and lipid concentrations (Tch, TG, HDL-c and LDL-c).‡ Empirical P values were calculated using 100,000 Monte Carlo simulations‖Multiple testing was adjusted by Bonferroni correctionAnalysis of Allelic Association of SNP rs9943582 with LVSD among the CAD population.

Freq_A：等位基因A的频率（Frequency of A allele）。LVSD：左心室收缩功能障碍（left ventricle systolic dysfunction），LVEF：左心室射血分数（left ventricular ejection fraction，原文此处写作left ventricle eject fraction，为不规范术语形式）。*未校正P值及比值比（OR）采用Pearson 2×2列联表卡方检验计算得到。†通过多因素logistic回归分析，对年龄、性别、吸烟、高血压、糖尿病及血脂指标[总胆固醇（Tch）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-c）、低密度脂蛋白胆固醇（LDL-c）]等潜在混杂因素进行校正后，得到校正P值。‡采用10万次蒙特卡洛模拟计算得到经验P值。‖采用Bonferroni校正法对多重检验进行校正。冠心病（Coronary Artery Disease, CAD）人群中单核苷酸多态性（Single Nucleotide Polymorphism, SNP）rs9943582的等位基因与LVSD的关联分析。