Chromatin remodeler INO80 mediates trophectoderm permeability barrier to modulate morula-to-blastocyst transition. Chromatin remodeler INO80 mediates trophectoderm permeability barrier to modulate morula-to-blastocyst transition

INO80 promotes blastocyst development through regulating expression of key genes required for lineage specification, tight junction assembly, and fluid accumulation. Overall design: Examination of 9 different samples about non-injected，control-siRNA injected and INO80-siRNA injected embryos

INO80通过调控谱系特化、紧密连接组装及体液积累所需关键基因的表达，促进囊胚发育。
实验设计概述：对未注射组、对照小干扰RNA（siRNA）注射组及INO80靶向siRNA注射组的9种不同胚胎样本开展检测。