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HTGTS for Linear RAG Scanning Mediates Editing of Igκ Variable Region Repertoires

ChEBI2026-02-23 更新2026-07-12 收录

V(D)J重组

免疫基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-16001 数据链接链接失效反馈

官方服务：

资源简介：

HTGTS for Linear RAG Scanning Mediates Editing of Igκ Variable Region Repertoires

应用场景：

创建时间：

2026-02-23

免疫基因组学

单核吞噬细胞功能

Primary RNASeq data for progenitor, resident, and stimulated (C.alb, LPS, injury, APAP+ starved overnight and pIC) mononuclear phagocytes from fourteen organs. Overall design: RNASeq data for over 400

NIAID Data Ecosystem80

Igk locus capture-based target enrichment sequencing. Igk locus capture-based target enrichment sequencing

V(D)J重组

DNA双链断裂修复

Cell cycle is a major determinant of DNA double-strand break (DSB) repair pathway choice with homologous recombination (HR) that is most active in S phase cells and non-homologous end-joining (NHEJ) t

NIAID Data Ecosystem50

Additional file 5: of Identification and analysis of divergent immune gene families within the Tasmanian devil genome

免疫基因组学

跨物种基因比较

Chemokine sequences identified in the Tasmanian devil genome. Description of data: Md % = percent amino acid identity to opossum (Monodelphis domestica) ortholog, Hs % = percent amino acid identity to

Figshare2016-12-16 更新30

The RAG-HMG1 Complex Enforces the 12/23 Rule of V(D)J Recombination Specifically at the Double-Hairpin Formation Step

V(D)J重组

淋巴细胞受体基因重组

A central unanswered question concerning the initial phases of V(D)J recombination has been at which step the 12/23 rule applies. This rule, which governs which variable (V), diversity (D), and joinin

PubMed Central70

Tasmanian devil MHC typing

免疫基因组学

保护遗传学

Genotyping of Tasmanian devils at MHC-I genes using PacBio long reads

NIAID Data Ecosystem30