Amide-Assisted Acetoxylation of Vinyl C(sp2)–H Bonds by Rhodium Catalysis

A direct regioselective acetoxylation of enamides has been accomplished using a combination of Cu­(OAc)2 and rhodium catalyst. Cu­(OAc)2 is served as the oxidant and also provides the source of acetate in the reaction.本研究成功实现了以乙酸铜(Cu(OAc)₂)与铑催化剂组合为催化体系的烯酰胺区域选择性直接乙酰氧基化反应。乙酸铜在此反应中既充当氧化剂，同时也提供了乙酰氧基源。