A Dual Lewis Base Activation Strategy for Enantioselective Carbene-Catalyzed Annulations
收藏NIAID Data Ecosystem2026-03-07 收录
数据链接：
官方服务：
资源简介：
A dual activation strategy integrating N-heterocyclic carbene (NHC) catalysis and a second Lewis base has been developed. NHC-bound homoenolate equivalents derived from α,β-unsaturated aldehydes combine with transient reactive o-quinone methides in an enantioselective formal [4 + 3] fashion to access 2-benzoxopinones. The overall approach provides a general blueprint for the integration of carbene catalysis with additional Lewis base activation modes.
创建时间：
2016-02-19
