Proportion of Participants Experiencing Safety Outcomes during the Trial.

CI = Confidence interval; DAIDS = Division of AIDS; RR = Risk ratio; STI = Sexually transmitted infection. Baseline was defined as pre-enrolment (Visit 1, Week 0) for pelvic/speculum and colposcopy assessments, adverse events, vaginal pH and vaginal flora assessments, and as screening visit for STI testing and safety laboratory tests. Point estimates and asymptotic 95% CIs are presented for the risk ratio comparing the proportion of women diagnosed with event post-baseline between the dapivirine ring and placebo ring arms.