EGFR Kinase domain T790M/L858R Mutant with TAK-285
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EGFR Kinase domain T790M/L858R Mutant with TAK-285 Descriptor: Epidermal growth factor receptor, N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide Authors: Sogabe, S, Kawakita, Y, Igaki, S. Deposit date: 2012-12-03 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors. Acs Med.Chem.Lett., 4, 2013
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2012-12-03
