Genome-wide CRISPR knockout screen to identify genes involved in macrophage differentiation

ChEBI2026-04-29 更新2026-07-12 收录

功能基因组筛选

巨噬细胞分化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-15740 数据链接链接失效反馈

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Genome-wide CRISPR knockout screen to identify genes involved in macrophage differentiation

创建时间：

2026-04-29

Table3_Integration of single-cell and bulk RNA-seq to establish a predictive signature based on the differentiation trajectory of M2 macrophages in lung adenocarcinoma.XLSX

癌症预后模型

巨噬细胞分化

Background: Tumor-associated macrophages as important members of the tumor microenvironment, are highly plastic and heterogeneous. TAMs can be classified into two preliminary subtypes: M1 and M2 macro

NIAID Data Ecosystem70

CRISPR/Cas9 mutagenesis screening identifies PRDM1 as a key regulator of the natural killer T cell central memory program and effector function. CRISPR/Cas9 mutagenesis screening identifies PRDM1 as a key regulator of the natural killer T cell central memory program and effector function

功能基因组筛选

NKT细胞免疫治疗

Natural killer T cells (NKTs) are a promising platform for cancer immunotherapy, but few genes involved in regulation of NKT therapeutic activity have been identified. To discover regulators of NKT fu

NIAID Data Ecosystem30

Plant of Solanaceae family used as a source of tobacco. Nicotiana tabacum

功能基因组筛选

烟草遗传转化

In order to learn the role of large numbers of genes (~20,000) a plant readily amenable to high-throughput transformation, plant propagation, and phenotypic screening was needed. Nicotiana tabacum, a

NIAID Data Ecosystem10

Data sheet index below 1.

功能基因组筛选

肿瘤代谢

In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a

Figshare2022-09-22 更新50

Gene expression profile at single cell level of total peritoneal cells from WT and HDC KO mouse

单细胞转录组学

巨噬细胞分化

Histamine is required for full differentiation of macrophage. We used single cell RNA sequencing(sc-RNA seq) to characterize the impairment of macrophage differentiation in HDC KO at molecular level.

Alliance of Genome Resources10

Genome-wide CRISPR knockout screen to identify genes involved in macrophage differentiation

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