Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

ChEBI2012-09-11 更新2026-07-21 收录

RNA剪接调控

癌细胞转移

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40737 数据链接链接失效反馈

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Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

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2012-09-11

RNA-seq of METTL4-mediated Nuclear N6-Deoxyadenosine Methylation Promotes Metastasis through Activating Multiple Metastasis-inducing targets. RNA-seq of METTL4-mediated Nuclear N6-Deoxyadenosine Methylation Promotes Metastasis through Activating Multiple Metastasis-inducing targets

RNA测序

癌细胞转移

Understanding the gene profiling in METTL4/6mA/RP11-390F4.3 axis. Overall design: Most of sample are replicates. For CRISPR-cont, METTL4-DPPW mutant clone1 and clone2 only once.

NIAID Data Ecosystem140

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癌细胞转移

内镜诊断

The gastrointestinal metastases of lung cancer（GMLC）is rare, but is more frequent than expected in patients with longer survival. In particular, the small intestinal metastases often have few or no sy

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The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation

RNA剪接调控

翻译控制

Recent work has associated point mutations in both zinc fingers (ZnF) of the spliceosome component U2AF35 with malignant transformation. However, surprisingly little is known about the functionality o

NIAID Data Ecosystem30

Data from: Origins of lymphatic and distant metastases in human colorectal cancer

癌细胞转移

结肠直肠癌

The spread of cancer cells from primary tumors to regional lymph nodes is often associated with reduced survival. One prevailing model to explain this association posits that fatal, distant metastases

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The impact of Prp18p on splicing fidelity and efficiency in budding yeast

剪接保真度

RNA剪接调控

Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that

Alliance of Genome Resources40

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

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