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DdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome

NIAID Data Ecosystem2026-03-13 收录

线粒体基因编辑

基因修饰表型分析

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP312050 数据链接链接失效反馈

官方服务：

资源简介：

PCR-Seq and ATAC-Seq data of DdCBE in mouse

应用场景：

创建时间：

2021-11-29

线粒体基因编辑

分子克隆

The PCR products from branched intermediates obtained with primers P2a and P3a specific for nad1e and primers P2b and P3b specific for nad5c were purified from agarose gel and cloned into pGEM-T, subs

Figshare2015-12-02 更新30

Overview of the phenotypes of Cebpa S248A/S248A and Cebpa KI/KI mice.

基因修饰表型分析

血液疾病模型

Overview of the phenotypes of CebpaS248A/S248A and CebpaKI/KI mice.

NIAID Data Ecosystem20

Additional file 3 of A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens

CRISPRi筛选

基因修饰表型分析

Supplementary Material 3

DataCite Commons2024-08-16 更新20

File S1 - Heritable Multiplex Genetic Engineering in Rats Using CRISPR/Cas9

CRISPR-Cas9基因编辑

基因修饰表型分析

Figure S1. The pUC57-sgRNA expression vector. The sgRNA expression vector was constructed using the backbone of the pUC57 vector with a Kanamycin resistance gene. The annealed oligos were inserted bet

Figshare2015-12-02 更新20

SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function [hMeDIP-Seq]

骨髓增生异常综合征干细胞调控

基因修饰表型分析

Improved understanding of mechanisms regulating myelodysplastic syndrome (MDS) hematopoietic stem/progenitor cell (HSPC) growth and self-renewal is critical for developing MDS therapy. We revealed a n

NIAID Data Ecosystem20

DdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome

资源简介：

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