官方服务：
资源简介：
To screen any driver mutations from human tissue by base editor
应用场景：
创建时间：
2020-10-06
相关数据集
Plant genome editing with different CBEs systems
Plant protoplast HTS data with different CBEs systems
NIAID Data Ecosystem70
Engineering of adenine base editor with improved editing activity across NNN PAMs. Homo sapiens
Engineering of adenine base editor with improved editing activity across NNN PAMs
NIAID Data Ecosystem60
Actionable driver oncogene mutations were excluded from neoadjuvant chemoimmunotherapy of non-small cell lung cancer
These known actionable driver oncogene mutations were excluded from neoadjuvant chemoimmunotherapy of non-small cell lung cancer in a retrospective cohort study, as they had corresponding target treat
NIAID Data Ecosystem10
Additional file 6: Table S5. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening
mRNA expression levels for kinases of top the 20 list for HCC-827 cells. Expression of candidate genes was found to be at very high level in the EGFR-mutant HCC-827 parental line, e.g. 128.09 FPKMs fo
Figshare2016-12-15 更新60
Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope. Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope
Base editors are RNA-guided deaminases that enable site-specific nucleotide transitions. The targeting scope of these Cas-deaminase fusion proteins critically depends on the availability of a protospa
NIAID Data Ecosystem40
