Several single-cell transcriptomic approaches have been applied to study immune system in MM, and previously implied “T-cell exhaustion” largely based on comparison with signatures derived in murine c

NIAID Data Ecosystem40

Replicative history marks transcriptional and functional disparity in the memory T cell pool

T细胞记忆

单细胞免疫组学

Mice received DivisionRecorder+ or unmodified OT-I T cells and were challenged with LM-OVA. During memory phase we FACS sorted memory CD8+ OT-I T cells (and sub-sorted RFP+ and RFP- cells in the case

NIAID Data Ecosystem70

Single-cell multiomics sequencing (RNA, ADT and VDJ) of CD4+ T cells from peripheral blood of CMV+ and CMV- healthy humans.. Single-cell multiomics sequencing (RNA, ADT and VDJ) of CD4+ T cells from peripheral blood of CMV+ and CMV- healthy humans.

单细胞免疫组学

T细胞克隆分析

The goal of this study is to understand the transcriptional features of CD4+ memory T cells induced by CMV seropositivity and explore their TCR repertoire clonality. Overall design: We selected CMV-as

NIAID Data Ecosystem50

scRNA-Seq of human MAIT cells sorted from PBMCs of pancreatic ductal adenocarcinoma patients and healthy controls

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