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Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome. Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome

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NIAID Data Ecosystem2026-03-11 收录
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To determine the individual and combined effects of excitotoxicity and overnutrition on beta-cell gene expression, we analyzed the impact of a high fat diet (HFD) on wild type C57Bl/6J and Abcc8 knockout mice of different sexes. We collected 31 bulk RNA-Seq datasets that originated from FACS-purified pancreatic beta-cells that differed by genotype, diet, and sex.

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2020-04-29
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