We determined nucleosome positions throughout the genome in diploid S. cerevisiae undergoing early stages of synchronous meiosis. This study sought to assess if systematic reorganization of nucleosome
It is well known that hypoxanthine (HX) inhibits nuclear maturation of oocytes by elevating the intracellular cAMP level, while melatonin (MT) is a molecule that reduces cAMP production, which may phy
Regulation of mRNA translation by cytoplasmic polyadenylation is known to be important for oocyte maturation and further development. This process is generally controlled by phosphorylation of cytopla
Bidirectional communication between mural granulosa cells (MGCs) and oocytes is crucial for oocyte maturation during mammalian follicular development. However, the underlying molecular networks remain
ESR2 mutant female rats are infertile. Oocyte maturation is defective in ESR2 mutants and they fail to ovulate . We are investigating the role of estrogen-signaling via ESR2 during gonadotropin-induce
