THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH AN ISOINDOLINONE INHIBITOR
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THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH AN ISOINDOLINONE INHIBITOR Descriptor: (1~{R})-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1 Authors: Casale, E, Papeo, G, Montagnoli, A. Deposit date: 2018-11-21 Release date: 2019-05-01 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515. Acs Med.Chem.Lett., 10, 2019
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2018-11-21
