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Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life

ChEBI2014-05-13 更新2026-07-21 收录

T细胞免疫记忆

发育免疫学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56575 数据链接链接失效反馈

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Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life

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2014-05-13

T细胞免疫记忆

感染免疫转录组学

Following infection with LCMV, CD4+ SMARTA TCR transgenic cells (specific for the gp61-80 epitope of the LCMV glycoprotein) rapidly expand, become effector cells, and go on to form a long-lived memory

NIAID Data Ecosystem120

CD8+ T-cell memory bears the transcriptional imprint of progressive differentiation. Mus musculus

T细胞免疫记忆

疫苗免疫应答

The generation of CD8+ T-cell memory is an important aim of immunization. While several distinct subsets of CD8+ T-cell memory have been described, the lineage relationships between effector (EFF), ef

NIAID Data Ecosystem80

Long-term T cell memory to human leucocyte antigen-A2 supertype epitopes in humans vaccinated against smallpox.

疫苗免疫表位鉴定

T细胞免疫记忆

The author describes the epitope as being derived from vaccinia virus Copenhagen. A blast search maps this epitope to variola major virus. 2/20 non-HLA-A2 supertype subjects also responded to this epi

ImmuneData40

Data from: Early exposure to a bacterial endotoxin advances the onset of moult in the European starling

鸟类换羽行为

发育免疫学

In animals, events occurring early in life can have profound effects on subsequent life-history events. Early developmental stresses often produce negative long-lasting impacts, although positive effe

DataONE2016-07-05 更新110

MORPHOLOGICAL AND HISTOGENETIC REMODELING OF THE SPLEEN IN POSTNATAL OFFSPRING BORN TO MOTHERS SUBJECTED TO CHRONIC EXPERIMENTAL STRESS

发育免疫学

产前应激病理学

Chronic stress during pregnancy is considered a significant risk factor that can negatively affect the development of organs and systems in offspring. The spleen, as a central immune organ, is particu

Zenodo2026-02-02 更新40

Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life

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