Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with IDI-6253
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Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with IDI-6253 Descriptor: 6-(3,4-dihydroisoquinolin-2(1H)-yl)-3-methyl-[1,2,4]triazolo[3,4-a]phthalazine, DIHYDROOROTATE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, ... Authors: Rowland, P. Deposit date: 2014-02-12 Release date: 2014-04-30 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.72 Å) Cite: In Vitro Resistance Selections for Plasmodium Falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-Binding Site and Altered Growth. J.Biol.Chem., 289, 2014
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2014-02-12
