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NANOG metabolically reprograms tumor-initiating stem-like cells in oxidative phosphorylation and fatty acid metabolism

ChEBI2016-01-07 更新2026-07-12 收录

癌细胞代谢

癌细胞重编程

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-68237 数据链接链接失效反馈

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资源简介：

NANOG metabolically reprograms tumor-initiating stem-like cells in oxidative phosphorylation and fatty acid metabolism

应用场景：

创建时间：

2016-01-07

癌细胞代谢

激酶信号通路

The 16 Supplementary Tables in the document provide information (including raw data) related to data throughout the manuscript

NIAID Data Ecosystem60

Model simulation results for 5 experiments on suspensions of Ehrlich ascites tumor cells in vitro.

癌细胞代谢

模型模拟

Experiment 1: low glucose concentration added (92 µM); Experiment 2: higher glucose concentration added (776 μM); Experiment 3: one hour aerobic incubation with high concentration of glucose (11.1 mM)

DataCite Commons2020-09-20 更新60

Crystal structure of human PHGDH complexed with Compound 15

PHGDH抑制剂结构

癌细胞代谢

Crystal structure of human PHGDH complexed with Compound 15 Descriptor: (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid, D-3-phosphoglycerate

Protein Data Bank Japan2024-11-06 更新40

Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

NIAID Data Ecosystem60

β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells

癌细胞代谢

SREBP信号通路调控

β-caryophyllene (BCP) exhibits anti-proliferative properties in cancer cells. Here, we examine the hypothesis that BCP induces membrane remodeling. Our data show that high concentrations of BCP incr

NIAID Data Ecosystem60

NANOG metabolically reprograms tumor-initiating stem-like cells in oxidative phosphorylation and fatty acid metabolism

资源简介：

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