Transcriptomic comparison of mouse lung adenocarcinoma cell lines derived upon treatment with urethane. Mus musculus

We repeatedly injected FVB and C57BL/6 intraperitonealy with urethane. Mice developed lung tumours. We sacrificed the mice, harvested their lungs and cultured the tumour cells. After over 60 passages we established 3 novel mouse lung adenocarcinoma cell lines. The aim of this study os to compare their transcriptomic profile. Overall design: We established 3 mouse lung adenocarcinoma cell lines, two from the FVB and one from the C57BL/6 background. All samples were analyzed using Genespring 12.5 GX to obtain the data.