人工心脏泵血液流场分析和改进的仿真计算数据集

轴流式心脏泵的流场中存在高剪切速率区，滞留区等异常流动区域。这些异常流动会导致心脏泵装置在植入后面临着严重的泵血栓形成问题，会导致植入的泵失效。本研究目的是利用多物理场仿真计算软件对轴流式心脏泵的流场进行分析，并将流场与凝血生化反应结合，通过血小板和凝血因子的浓度变化分析心脏泵的血栓形成过程和机理。
超声微泡联合作用除栓的微观机理研究需要体外构建成分含量不同的血栓。本研究目的是利用微流控技术，结合不同类型血管形状，计算流道中对应的剪切速率和剪切力分布，为体外探索超声微泡联合作用除栓的微观机理提供平台。本仿真计算数据集由心脏泵的计算数据文件和微流控平台数据处理文件组成。
心脏泵的计算数据文件由3部分组成：
（a）心脏泵的流场计算文件：根据仿真软件ANSYS计算所得，计算了在不同转速和不同的流量条件下心脏泵的流场。
（b）基于流场分析后改进的心脏泵的流场计算文件：根据仿真软件ANSYS计算所得，计算了在不同转速和不同的流量条件下改进后的心脏泵的流场。
（c）基于流场的心脏泵前导叶血栓形成仿真计算结果：根据仿真软件COMSOL计算所得，建立了基于流动和血小板及凝血相关物质的浓度变化的血栓形成模型，计算了在不同的流量条件下前导叶的血栓形成过程。
微流控平台数据处理文件包括荧光粒子在流道中的运动视频、DUNAMIC STUDIO处理后的dat.文件以及TECPLOT软件导出的数据图。

There are abnormal flow regions including high shear rate zones and stagnant zones in the flow field of axial flow heart pumps. These abnormal flows will cause the heart pump device to face severe pump thrombosis after implantation, leading to failure of the implanted pump. The objective of this study is to analyze the flow field of the axial flow heart pump using multiphysics simulation software, combine the flow field with blood coagulation biochemical reactions, and elucidate the process and mechanism of thrombosis formation in the heart pump by monitoring the concentration changes of platelets and coagulation factors.

The research on the micro-mechanism of ultrasound microbubble combined thrombolysis requires in vitro construction of thrombi with varying component contents. The purpose of this study is to utilize microfluidic technology combined with different types of blood vessel geometries to calculate the corresponding shear rate and shear force distributions in the flow channel, providing a platform for in vitro investigation of the micro-mechanism of ultrasound microbubble combined thrombolysis. This simulation dataset comprises two categories of files: computational data files for the heart pump and data processing files for the microfluidic platform.

The computational data files for the heart pump consist of three parts:
(a) Heart pump flow field calculation files: Calculated using the ANSYS simulation software, the flow fields of the original heart pump under different rotational speeds and flow rates were obtained.
(b) Improved heart pump flow field calculation files based on flow field analysis: Calculated using the ANSYS simulation software, the flow fields of the improved heart pump under different rotational speeds and flow rates were obtained.
(c) Simulation results of thrombosis formation in the leading guide vane of the heart pump based on flow field: Using the COMSOL simulation software, a thrombosis formation model based on flow dynamics and concentration changes of platelets and coagulation-related substances was established, and the thrombosis formation process of the leading guide vane under different flow rates was calculated.

The data processing files for the microfluidic platform include motion videos of fluorescent particles in the flow channel, .dat files processed by DUNAMIC STUDIO, and exported data plots generated by TECPLOT software.

搜集汇总

背景与挑战

背景概述

该数据集聚焦于人工心脏泵的血液流场仿真计算，旨在通过多物理场软件分析轴流式心脏泵的流场特性，研究血栓形成机理并改进泵设计，以解决泵血栓问题。数据集包含心脏泵在不同条件下的流场计算、改进后流场计算以及血栓形成仿真结果，同时提供微流控平台数据处理文件，用于体外探索超声微泡除栓机理。数据由清华大学发布，总数据量为10.32GB，涵盖937个文件，适用于外科学和应用力学领域的研究。