Changes in original Grandi et al. (GPB) [34] and O'Hara et al. (ORd) [35] models to simulate heart failure (HF) phenotype. The modified parameters are: the late Na+ current (INaL), the time constant o
Ectopic heartbeats can trigger reentrant arrhythmias, leading to ventricular fibrillation and sudden cardiac death. Such events have been attributed to perturbed Ca2+ handling in cardiac myocytes lead
Accompanying OMEX file for the Physiome article "Reproducibility study of the Fabbri et al. 2017 model of the human sinus node action potential".An OMEX archive is the Open Modelling Exchange format,
Biophysically detailed mathematical models of cardiac electrophysiology provide an alternative to experimental approaches for investigating possible ionic mechanisms underlying the genesis of electric
