Beneficial effects of vascular endothelial growth factor B gene transfer in aged heart

ChEBI2024-11-30 更新2026-07-12 收录

心血管基因治疗

衰老心脏病理

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-14595 数据链接链接失效反馈

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Beneficial effects of vascular endothelial growth factor B gene transfer in aged heart

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2024-11-30

Repression of Cardiac Hypertrophy by KLF15: Underlying Mechanisms and Therapeutic Implications

心脏肥大机制研究

心血管基因治疗

The Kruppel-like factor (KLF) family of transcription factors regulates diverse cell biological processes including proliferation, differentiation, survival and growth. Previous studies have shown tha

NIAID Data Ecosystem50

Effect of intramyocardial WDR12 gene delivery on cardiac structure and function in normal adult rat hearts, post-infarction, and in angiotensin II-induced hypertension at 1 week.

心血管基因治疗

心电图评估

MI, myocardial infarction; Ang II, angiotensin II; LV, left ventricular; IVRT, isovolumic relaxation time Adenoviral gene construct expressing WDR12 and LacZ were injected into LV free wall and echoca

NIAID Data Ecosystem30

衰老小鼠模型中心肌线粒体形态变化1

衰老心脏病理

线粒体形态学

衰老及年轻小鼠每组50只，其中各5只用于检测功能，其余用于线粒体形态、功能等检测见下）透射电镜拍照采集数据，根据形态判断线粒体大小、数量、形态及线粒体自噬小体。采用透射电镜观察和拍照进行线粒体数量和形态的观察，本数据集用论文和科学项目。

国家人口健康科学数据中心20

Cardiac-targeted AAV5-S100A1 gene therapy protects against adverse remodeling and contractile dysfunction in post-ischemic herats

心血管基因治疗

心肌修复机制

Background: Guided by long-term safety data for AAV5 in humans, our translational study investigated whether AAV5 effectively delivers genes to healthy and achieve therapeutic efficacy in dysfunctiona

NIAID Data Ecosystem50

Beta-Adrenergic gene therapy for cardiovascular disease

心血管基因治疗

β-肾上腺素能受体信号调控

Gene therapy using in vivo recombinant adenovirus-mediated gene transfer is an effective technique that offers great potential to improve existing drug treatments for the complex cardiovascular diseas

PubMed Central2000-10-20 更新30

Beneficial effects of vascular endothelial growth factor B gene transfer in aged heart

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