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资源简介：
Use igRNA and ABE to reduce Bystander editing
应用场景：
创建时间：
2022-03-25
相关数据集
RNA-seq for off-target of RESCUE-S and CURE
Various editors were co-expressed in HEK293T cells with the GFP reporter transcript and the corresponding gRNAs (28-14 and 30/22 for CURE and RESCUE-S, respectively) before on-target editing at the re
NIAID Data Ecosystem60
Td-BE-NGS-7
Genome-wide distribution of off-target effects determined by Detect-seq and unbiased sgRNA-target pair library analysis of indicated CBEs
NIAID Data Ecosystem30
Cytosine base editing systems with minimized off-target effect and molecular size
The sequence data were generated in order to evaluate the performance of CBE (cytosine base editor) variants Target-AID2S,3S in comparison with CBE variants Target-AID, YE1, YE2, and R33A+K34A.
NIAID Data Ecosystem20
Additional file 5: Table S2. of An efficient system for homology-dependent targeted gene integration in medaka (Oryzias latipes)
The numbers of potential off-target sequences in reference genomes of teleost fish species. Numbers of genomic sites with up to 3Â bp mismatches in the total 21Â bp sequences are shown. (XLSX 11 kb)
Figshare2017-07-07 更新50
Cas9 interactions with host RNAs and transposable elements impair neurodevelopment (RNA-seq). Cas9 interactions with host RNAs and transposable elements impair neurodevelopment (RNA-seq)
The CRISPR (clustered regulatory interspaced short palindromic repeats)/ Cas9 (CRISPR-associated protein 9) system-based precise genome editing has revolutionized biomedical studies. As the CRISPR/Cas
NIAID Data Ecosystem20
