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Use igRNA and ABE to reduce Bystander editing
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创建时间:
2022-03-25
相关数据集
Putative off-target sites of Ar-A and Ar-B sgRNAs.
Putative off-target sites of Ar-A and Ar-B sgRNAs.
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Additional file 10 of The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model
Additional file 10: Table S8. Transcriptome profiles of HEK293T transfected of RfxCas13d, NeuN and crRNA (Linked to Response Fig. 8 of first revision).
Figshare2024-02-07 更新40
Deep sequencing of 8 off-target sites detected by WGS
We successfully develop a two-in-one approach to generate non-viral genome specific targeted CAR T cells through CRISPR/Cas9. In the adoptive therapy for relapsed/refractory aggressive B-cell non-Hodg
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Predictability of DdCBEs mediated base editing in mitochondrial DNA
DdCBE acts as the most commonly used editor for mtDNA, our understanding of the editing rules is very limited, especially for the aC targets, we need to optimize the editing strategies by adjusting th
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