86b5b04d-1d30-4917-afb8-07d018a57901 - samples

NIAID Data Ecosystem2026-03-13 收录

iPSC

运动神经元

数据链接：

https://www.omicsdi.org/dataset/ega/EGAD00001008427 数据链接链接失效反馈

官方服务：

资源简介：

iPSC-derived motor neurons from 5 NOVA1 knock out and 5 NOVA1 wt lines in the CVB background.EGA dataset EGAD00001008427

创建时间：

2022-06-02

C9ORF72基因HRE敲入大鼠

基因敲入

运动神经元

HRE敲入大鼠体重和生殖能力正常，但与野生型大鼠相比，免疫器官有改变，脾脏无明显变化，胸腺显著减小，颈部淋巴结明显增大。外周血流式分析显示4月龄的HRE敲入大鼠中性粒细胞比例显著上升，淋巴细胞中CD3、CD4均显著降低。至12个月龄，未发现其他器官有明显缺陷。与WT相比KI大鼠12M时运动协调和肢体力量下降分别为68%和56%。雌性KI大鼠在13-24M年龄段后肢麻痹发生率为25%(5/20)。这

中国科技资源共享网2026-08-02 更新140

HipSci_30x_whole_genome_sequencing_of_iPSC_reference_set. HipSci_30x_whole_genome_sequencing_of_iPSC_reference_set

基因组测序

iPSC

The HipSci project brings together diverse constituents in genomics, proteomics, cell biology and clinical genetics to create a UK national iPS cell resource and use it to carry out cellular genetic s

NIAID Data Ecosystem50

IPS research publications list

出版研究

iPSC

A list of research publications published by IPS.

data.gov.uk2014-05-10 更新50

iPSCORE_kinship.txt

遗传学

iPSC

Kinship matrix for iPSCORE individuals

DataCite Commons2023-04-17 更新70

RNA sequencing of MShef11 WT, MFN2R94Q/+, MFN2 R94Q/R94Q differentiated to limb innervating motor neurons. RNA sequencing of MShef11 WT, MFN2R94Q/+, MFN2 R94Q/R94Q differentiated to limb innervating motor neurons

CMT2A疾病模型

运动神经元

We have generated CRISPR edited versions of hESC line MShef11 to produce MFN2 R94Q/+ and MFN2 R94Q/R94Q lines as a model for Charcot Marie Tooth Disease (CMT) 2A. This were differentiated to limb inne

NIAID Data Ecosystem50

86b5b04d-1d30-4917-afb8-07d018a57901 - samples

资源简介：

相关数据集