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Identification of differentially expressed genes due to LBH589 treatment in aromatase inhibitor-resistant tumors

ChEBI2014-03-10 更新2026-07-21 收录

肿瘤耐药性基因表达

抗癌药物靶点识别

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-47346 数据链接链接失效反馈

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资源简介：

Identification of differentially expressed genes due to LBH589 treatment in aromatase inhibitor-resistant tumors

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创建时间：

2014-03-10

蛋白结构预测

抗癌药物靶点识别

MEK1 is a protein kinase in the MAPK cellular signaling pathway that is notable for its dual specificity and its potential as a drug target for a variety of cancer therapies. While much is known about

NIAID Data Ecosystem70

FBA03-TRCA-Model-CandEnzRxn-CABL-Wt-Rxn.gms is used to estimate a set of candidate enzymes and reactions. from Fuzzy optimization for identifying anti-cancer targets with few side effects in constraint-based models of head and neck cancer

抗癌药物靶点识别

头颈癌代谢模型优化

Computer-aided methods can be used to screen potential candidate targets and to reduce the time and cost of drug development. In most of these methods, synthetic lethality is used as a therapeutic cri

Figshare2022-10-21 更新50

Identification of differentially expressed genes due to LBH589 treatment in aromatase inhibitor-resistant tumors

肿瘤耐药性基因表达

药物基因组学

In order to validate the utility of a novel pathway algorithm (BD-Func), we test if an LBH589 signature based data from 3 cell lines (GSE36509) in an independent experiment in vivo. Xenograft tumor tr

NIAID Data Ecosystem30

Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a

结构生物学

抗癌药物靶点识别

Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-

Protein Data Bank Japan2023-11-29 更新50

Human protein farnesyltransferase complexed with L-778,123 and FPP

蛋白质法尼基转移酶抑制剂

抗癌药物靶点识别

Human protein farnesyltransferase complexed with L-778,123 and FPP Descriptor: 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE, FARNESYL DIPHOSPHATE, Protei

Protein Data Bank Japan2023-08-23 更新40

Identification of differentially expressed genes due to LBH589 treatment in aromatase inhibitor-resistant tumors

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