Myocardial I/R injury models were established using SPF-grade male Sprague-Dawley (SD) rats, randomly divided into control, I/R, and I/R+Nicorandil groups (n=6 per group). The I/R+Nicorandil group, ni
a. Baseline. b. Perfusion 30 min. c. Perfusion 120 min. Retrograde perfusion of the hearts was performed in a non-recirculating Langendorff apparatus with. A latex balloon was placed in the left ventr
Introduction: Moderate hydrogen peroxide postconditioning (H2O2PoC) activates signal transducer and activator of transcription 3 (STAT3) to alleviate mitochondrial calcium overload during cardiac isch
Background: The mechanisms underlying myocardial ischemia/reperfusion (I/R) injury are not fully understood. This study aims to explore key candidate genes and potential therapeutic targets for treatm
