Comparison of the quality of models describing etoposide exposure.

NIAID Data Ecosystem2026-05-02 收录

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https://figshare.com/articles/dataset/Comparison_of_the_quality_of_models_describing_etoposide_exposure_/28569403 数据链接链接失效反馈

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资源简介：

Comparison of the quality of models describing etoposide exposure.

创建时间：

2025-03-10

Selectivity: Drugs concomitantly administered with ifosfamide.

药物相互作用分析

药代动力学评估

The concentration of each drug was determined according to which it is administered in clinical practice. SD: Standard Deviation calculated from three independent repeats (n = 3). Selectivity: Drugs c

NIAID Data Ecosystem60

Plasma and brain exposure of Sch-58261 and Co-101244 administered alone or in combination.

药代动力学评估

中枢神经系统药物分布

Results expressed as mean ± standard deviation of three animals.aBoth compounds were delivered ip at 3 mg/kg with samples obtained 90 min after dosing.bConcentrations expressed per g tissue.Plasma and

Figshare2015-12-02 更新30

An Open-label, Single-dose Study to Assess the Pharmacokinetics, Safety and Tolerability of Quizartinib in Subjects With Moderate Impaired Hepatic Function as Defined by NCI-ODWG Criteria

药代动力学评估

特殊人群用药研究

Quizartinib is a novel oral Class III receptor tyrosine kinase (RTK) inhibitor exhibiting highly potent and selective but reversible inhibition of Feline McDonough sarcoma (FMS)-like tyrosine kinase 3

DataCite Commons2025-04-23 更新10

ADME properties of screened anticancer molecules of natural and synthetic origin docked onto human FN3K model protein [23].

抗癌药物分子对接

药代动力学评估

ADME properties of screened anticancer molecules of natural and synthetic origin docked onto human FN3K model protein [23].

NIAID Data Ecosystem30

Bioavailability and exposure fraction (AUCinf) of I2S in the serum and CSF after IT-L dosing.

神经药物递送

药代动力学评估

AUCinf, area under the concentration-time curve extrapolated to infinity; CM, cisterna magna; CSF, cerebrospinal fluid; EF, exposure fraction; F, bioavailability; I2S, iduronate-2-sulfatase; IT-L, int

Figshare2015-12-03 更新20

Comparison of the quality of models describing etoposide exposure.

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