Craniofacial microsomia (CFM) is a common congenital condition (1:3,500) that affects the facial skeleton, ears, and facial nerve among other facial and extracranial malformations. As a result, childr
Using CRISPR/Cas9, we generated a _Dspp_^−1fs^ mouse model by introducing a FLAG-tag followed by a single nucleotide deletion that translated 493 extraneous amino acids before termination. Developing
Researching what miRNAs are expressed in the E14.5 mouse midfacial tissue. Methods: * 1 dissected maxillas (4 mg w/w per maxilla; 4.0 ug of purified miRNA) * 6 dissected palatal shelves (1.5-2 mg w/w
This dataset includes microCT scans of the head tissue of Wnt1-Cre;Alk5fl/fl (YC389CCMB) at P0. The scans are in NiFTI format, which can be read by a number of free software applications including tho
This dataset includes the results of RNA-Seq analysis in E13.5 mouse palates. The downloadable Excel file includes for each gene: * gene: official mouse gene symbol * gene length (bp, exons only) * RP
