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Single cell sequencing of the germinal center B cell receptor repertoire of NP-KLH immunized Cxcl13-Cre/Cxcl12fl/fl and control mice

ChEBI2020-05-12 更新2026-07-12 收录

单细胞免疫组学

生发中心B细胞研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-8904 数据链接链接失效反馈

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资源简介：

Single cell sequencing of the germinal center B cell receptor repertoire of NP-KLH immunized Cxcl13-Cre/Cxcl12fl/fl and control mice

应用场景：

创建时间：

2020-05-12

单细胞免疫组学

受体分析

This TCR dataset was generated using the Cell Ranger 6.0 pipeline, with no modifications other than the addition of a sample name to each barcode.

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Replicative history marks transcriptional and functional disparity in the memory T cell pool

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Mice received DivisionRecorder+ or unmodified OT-I T cells and were challenged with LM-OVA. During memory phase we FACS sorted memory CD8+ OT-I T cells (and sub-sorted RFP+ and RFP- cells in the case

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Immune-aging is linked to clinical malignancy and vaccine responses in myeloma. Immune-aging is linked to clinical malignancy and vaccine responses in myeloma

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Several single-cell transcriptomic approaches have been applied to study immune system in MM, and previously implied “T-cell exhaustion” largely based on comparison with signatures derived in murine c

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Single cell RNA Sequencing of term maternal PBMC at delivery from lean mothers and mothers with obesity

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A healthy pregnancy is associated with dynamic changes in the maternal immune system that facilitates placentation, fetal growth, fetal tolerance, and labor. Pre-pregnancy obesity is associated with s

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Single-cell multiomics sequencing (RNA, ADT and VDJ) of CD4+ T cells from peripheral blood of CMV+ and CMV- healthy humans.. Single-cell multiomics sequencing (RNA, ADT and VDJ) of CD4+ T cells from peripheral blood of CMV+ and CMV- healthy humans.

单细胞免疫组学

T细胞克隆分析

The goal of this study is to understand the transcriptional features of CD4+ memory T cells induced by CMV seropositivity and explore their TCR repertoire clonality. Overall design: We selected CMV-as

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Single cell sequencing of the germinal center B cell receptor repertoire of NP-KLH immunized Cxcl13-Cre/Cxcl12fl/fl and control mice

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