Replication and combined analysis of the most significant SNPs.

Abbreviations: CMH = Cochran-Mantel-Haenszel test, BD = Breslow-Day test, OR = Odds ratio, CI = Confidence interval. (1)The risk alleles (with respect to the Basque dataset) are underlined. (2)The ORs are represented for the risk alleles found in the first-stage screen. (3)rs11230563 was included because it is a non-synonymous SNP that substitutes R225W, and showed a trend towards association in the first stage screen. (4)rs650258 was included based on the association observed in the Basque dataset.