Copper (Cu) regulates hypoxia-inducible factor-1 (HIF-1) transcription activity by affecting the selectivity of HIF-1α targeting to the promoters of the affected genes. Here, we made an effort to prov

NIAID Data Ecosystem50

Effects of exposure to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine on HTR-8/SVneo differential gene expression under hypoxic vs. normoxic conditions (O2 < 2%). Effects of exposure to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine on HTR-8/SVneo differential gene expression under hypoxic vs. normoxic conditions (O2 < 2%)

细胞毒性机制

缺氧应激基因表达调控

Trichloroethylene (TCE) is an industrial solvent and widespread environmental contaminant. Human TCE exposure is prevalent, though epidemiological studies testing TCE exposure and adverse birth outcom

NIAID Data Ecosystem30

Transcriptome analysis using Quant-RNAseq after NPM1 or HIF-1a silencing under normoxia or Hypoxia

缺氧应激基因表达调控

转录基因沉默

Hypoxia inducible factor-1 (HIF-1) is a central transcriptional regulator of genes associated with adaptive responses to hypoxia. NPM1 is a histone chaperone found to associate with HIF-1a in a phosph

NIAID Data Ecosystem70

Quantitative gene expression data of hypoxia experimental data sets

缺氧应激基因表达调控

定量基因组学

Quantitative gene expression data of hypoxia experimental data sets using ikra (coding gene)

Figshare2021-03-02 更新40