HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5
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HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5 Descriptor: 1-[4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl]-3-{[(R)-(2,4-dimethylphenyl)(methoxy)phosphoryl]amino}-1H-pyrazole-4-carboxylic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... Authors: Pierra, C, Dousson, C, Augustin, M. Deposit date: 2015-07-31 Release date: 2016-06-15 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase. Bioorg.Med.Chem.Lett., 26, 2016
创建时间：
2015-07-31
