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Tuberous sclerosis complex 1 (Tsc1) enforces quiescence of naive T cells to promote immune homeostasis and function

ChEBI2011-07-11 更新2026-07-21 收录

T细胞免疫调节

免疫稳态机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-29797 数据链接链接失效反馈

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Tuberous sclerosis complex 1 (Tsc1) enforces quiescence of naive T cells to promote immune homeostasis and function

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创建时间：

2011-07-11

单细胞转录组学

T细胞免疫调节

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem80

ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis [single cell RNA-seq]

T细胞免疫调节

单细胞转录组学

RNA binding proteins (RBP) of the ZFP36 family limit the differentiation and effector functions of CD4 and CD8 T cells, but little is known of their expression or function in regulatory T cells (Treg)

NIAID Data Ecosystem50

Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer [microarray]

单细胞基因组学

T细胞免疫调节

The gene regulatory network (GRN) underlying CTL differentiation and whether Tex responses can be functionally reinvigorated are incompletely understood. Here, we systematically mapped causal GRNs via

NIAID Data Ecosystem30

Effect of Disulfiram on T cell activation

T细胞免疫调节

药物机制研究

To determine the effect of DSF on T cell activation ,we treated T cells with DSF and analyzed their functions. Comparative gene expression profiling analysis of RNA-seq for T cells after treated with

NIAID Data Ecosystem60

Transcriptome analysis of antigen-specific T follicular helper (Tfh) and non-Tfh cells after Bach2 overexpression. Transcriptome analysis of antigen-specific T follicular helper (Tfh) and non-Tfh cells after Bach2 overexpression

T细胞免疫调节

转录组学分析

We identified Bach2 as factor to be expressed at low levels in Tfh cells. Induced overexpression of Bach2 in the germinal center reaction results in loss of the Tfh cell population. RNA-seq of sorted

NIAID Data Ecosystem40

Tuberous sclerosis complex 1 (Tsc1) enforces quiescence of naive T cells to promote immune homeostasis and function

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