SARS-CoV-2, the causative agent of the COVID-19 pandemic, drastically modifies the cells that it infects. One such effect is the activation of the host p38 mitogen-activated protein kinase (MAPK) path
Ground state sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat Descriptor: Apical region (29-mer) of the HIV-1
Porcine deltacoronavirus (PDCoV) is an emerging pathogen that can cause severe diarrhoea and high mortality in suckling piglets. Moreover, evidence of PDCoV infection in humans has raised concerns reg
We performed a genome-wide CRISPR knockout screen to identify human genes required for SARS-CoV-2 infection. Overall design: Human Huh7 CRISPR-Cas9 perturbed cells were infected with SARS-CoV-2 at low
Aim: The aim of this study was to identify host factors that interact with the 5? end of the MERS-CoV RNA genome. Materials & methods: RNA affinity chromatography followed by mass spectrometry ana
