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资源简介：
Type-I interferon response profiling
应用场景：
创建时间：
2014-03-13
相关数据集
STAT3 Inhibits Autocrine Interferon Signaling in Type I Conventional Dendritic Cells
Type I conventional dendritic cells (cDC1s) are an essential antigen-presenting population, required for generating adaptive immunity against intracellular pathogens and tumors. While the transcriptio
NIAID Data Ecosystem60
IKK-epsilon regulates the balance between the type I and type II interferon responses. Mus musculus
Virus infection induces the production of type I and type II interferons (IFN-I and IFN-II), cytokines that mediate the antiviral response. IFN-I (IFN-a and -b) induces the assembly of ISGF3 (interfer
NIAID Data Ecosystem20
MDA5-binding interferon-inducible RNA sequencing
The goal is to assess whether interferon-inducible RNA regulates type I IFN through cytosolic RNA sensor MDA5. Huh7 cells were treated with or without IFN beta. Anti-MDA5 immunoprecipitation was condu
NIAID Data Ecosystem20
Engagement of the Cellular Receptor for Glycoprotein B of Human Cytomegalovirus Activates the Interferon-Responsive Pathway
Cells respond to contact with human cytomegalovirus (HCMV) virions by initiating intracellular signaling and gene expression characteristic of the interferon (IFN)-responsive pathway. Herein, we demon
PubMed Central20
Regulatory Role of SLFN5 in Type I Interferon Signaling
We provide evidence that a member of the IFN-regulated member of the Schlafen (SLFN) family of proteins, SLFN5, promotes the malignant phenotype in glioblastoma multiforme (GBM). Our studies demonstr
NIAID Data Ecosystem20
