Crystal structure of the guide-strand-containing Argonaute protein silencing complex

NIAID Data Ecosystem2026-05-01 收录

Argonaute蛋白

RNA干扰机制

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Crystal structure of the guide-strand-containing Argonaute protein silencing complex

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2024-02-21

The structure of human Argonaute-2 in complex with miR-20a

蛋白质-RNA复合物结构

RNA干扰机制

Argonaute proteins lie at the heart of the RNA-Induced Silencing Complex (RISC), wherein they use small RNA guides to recognize targets. Some Argonaute proteins can directly cleave their targets, wher

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Structural insights into small RNA sorting and mRNA binding by Arabidopsis Ago domains

RNA干扰机制

蛋白质-RNA相互作用

Structural insights into small RNA sorting and mRNA binding by Arabidopsis Ago domains Descriptor: Protein argonaute 1, SULFATE ION Authors: Yuan, Y.A, Zha, X. Deposit date: 2012-01-11 Release date: 2

Protein Data Bank Japan2024-03-20 更新40

Slicer activity of Arabidopsis AGO1 in siRNA biogenesis and miRNA target decay. Slicer activity of Arabidopsis AGO1 in siRNA biogenesis and miRNA target decay

RNA干扰机制

基因表达调控

Aim of study The objective of these studies was to analyze the implication of slicer activity of AGO1 in the following molecular processes: • loading of siRNAs and miRNAs • stability of siRNAs and miR

NIAID Data Ecosystem30

DEPS-1 promotes P granule assembly and RNA interference in C. elegans germ cells

昆虫生殖细胞发育

RNA干扰机制

P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss

Alliance of Genome Resources50

Argonaute 2-2 Associated small RNAs

RNA干扰机制

植物病原体小RNA

RNA-Seq of small RNAs that co-precipitate with the Argonaute 2-2 protein in virulent E. histolytica strain HM1:IMSS and small RNAs from the avirulent strain Rahman. At views > 3kb a plot o

NIAID Data Ecosystem40

Crystal structure of the guide-strand-containing Argonaute protein silencing complex

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