Synthesis of Indeno[1,2‑<i>c</i>]furans via a Pd-Catalyzed Bicyclization of 2‑Alkynyliodobenzene and Propargylic Alcohol
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A general and efficient synthesis of indeno[1,2]furans via a Pd-catalyzed bicyclization reaction between 2-alkynyliodobenzenes and propargylic alcohols is described. The procedure furnishes indeno[1,2]furans with moderate to excellent yields (51%–78%) and a broad substrate scope. The cascade process combines the formation of one C–O bond and two C–C bonds in a single step.
创建时间：
2012-12-21
