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Slamseq of whole mouse primary cortical neurons (mPCN) with perturbed mRNA degradation machinery

ChEBI2022-11-14 更新2026-07-12 收录

RNA代谢动力学

神经元基因调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11575 数据链接链接失效反馈

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Slamseq of whole mouse primary cortical neurons (mPCN) with perturbed mRNA degradation machinery

应用场景：

创建时间：

2022-11-14

神经元基因调控

干细胞分化

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Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast - 4tU cordycepin treatment

转录后调控

RNA代谢动力学

mPAT approach using an anchored oligo-dT (TV12VN) primer to determine changes to 3'UTR length in yeast upon cordycepin treatment and new transcription using 4-thiouracil (4tU) labelling of RNA. This a

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Additional file 1: of Circular RNA expression and regulatory network prediction in posterior cingulate astrocytes in elderly subjects

环状RNA表达

神经元基因调控

Table S1. Master summary of all detected circRNAs (XLSX 559Â kb)

Figshare2018-05-09 更新30

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms. Mus musculus

神经元基因调控

TOP1切割复合物机制

Topoisomerase 1 (TOP1) inhibitors, including camptothecin and topotecan, covalently trap TOP1 on DNA, creating cleavage complexes (cc’s) that must be resolved before gene transcription and DNA replica

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Thiol-linked alkylation for the metabolic sequencing of RNA [SLAM-seq of wildtype mES cell RNA +/- iodoacetamide treatment]. Mus musculus

RNA代谢动力学

基因表达动态

Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady-state but obscures the intracellular dynamics of RNA transcription, proces

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Slamseq of whole mouse primary cortical neurons (mPCN) with perturbed mRNA degradation machinery

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