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To understand the transcriptome change in astrocytes after parental isolation
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Table_5_Common Dysregulation of Innate Immunity Pathways in Human Primary Astrocytes Infected With Chikungunya, Mayaro, Oropouche, and Zika Viruses.xlsx
Arboviruses pose a major threat throughout the world and represent a great burden in tropical countries of South America. Although generally associated with moderate febrile illness, in more severe ca
NIAID Data Ecosystem690
Gene expression data from iPSC-derived astrocytes, comparison. Homo sapiens
Alexander disease (AxD) is a fatal neurological illness characterized by white-matter degeneration and formation of Rosenthal fibers, which contain glial fibrillary acidic protein (GFAP) as astrocytic
NIAID Data Ecosystem60
T cell-specific deletion of TRAIL-receptor reveals a critical role for pathologic T cell activation and inflammation in experimental autoimmune encephalomyelitis
We isolated CD4 T cells from EAE mice with or without TRAIL treatment and analyzed by RNA-seq. We also activated naïve CD4 T cells by anti-CD3/CD28 antibodies in the presence or absence of TRAIL and s
DataMed40
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and tri-glial dysfunctions
The majority of patients with amyotrophic lateral sclerosis (ALS) have abnormal TDP-43 aggregates in the nucleus and/or cytosol of their surviving neurons and glia. Although accumulating evidence indi
NIAID Data Ecosystem80
Genome-wide characterization of CREB-dependent transcriptional programs in astrocytes
Transcriptome profiling of astrocyte cultures treated with forskolin (FSK), noradrenaline (NE) or infected with adenovirus carrying a constitutively active form of CREB (VP16-CREB) vs. untreated or in
NIAID Data Ecosystem60
